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circMAP3K4 regulates insulin resistance in trophoblast cells during gestational diabetes mellitus by modulating the miR-6795-5p/PTPN1 axis

BACKGROUND: Insulin resistance (IR) during gestational diabetes mellitus (GDM) has been linked to dysregulated insulin-PI3K/Akt pathway. A defective insulin-PI3K/Akt pathway and dysregulated circular RNA (circRNA) levels have been observed in the placentas of patients with GDM; however, the mechanis...

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Detalles Bibliográficos
Autores principales:	Du, Runyu, Wu, Na, Bai, Yu, Tang, Lei, Li, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022258/ https://www.ncbi.nlm.nih.gov/pubmed/35449053 http://dx.doi.org/10.1186/s12967-022-03386-8

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