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Subfamily-specific differential contribution of individual monomers and the tether sequence to mouse L1 promoter activity
BACKGROUND: The internal promoter in L1 5’UTR is critical for autonomous L1 transcription and initiating retrotransposition. Unlike the human genome, which features one contemporarily active subfamily, four subfamilies (A_I, Gf_I and Tf_I/II) have been amplifying in the mouse genome in the last one...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022269/ https://www.ncbi.nlm.nih.gov/pubmed/35443687 http://dx.doi.org/10.1186/s13100-022-00269-z |