Subfamily-specific differential contribution of individual monomers and the tether sequence to mouse L1 promoter activity

BACKGROUND: The internal promoter in L1 5’UTR is critical for autonomous L1 transcription and initiating retrotransposition. Unlike the human genome, which features one contemporarily active subfamily, four subfamilies (A_I, Gf_I and Tf_I/II) have been amplifying in the mouse genome in the last one...

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Detalles Bibliográficos
Autores principales: Kong, Lingqi, Saha, Karabi, Hu, Yuchi, Tschetter, Jada N., Habben, Chase E., Whitmore, Leanne S., Yao, Changfeng, Ge, Xijin, Ye, Ping, Newkirk, Simon J., An, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022269/
https://www.ncbi.nlm.nih.gov/pubmed/35443687
http://dx.doi.org/10.1186/s13100-022-00269-z

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