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Identifying causal genes for stroke via integrating the proteome and transcriptome from brain and blood

BACKGROUND: Genome-wide association studies (GWAS) have revealed numerous loci associated with stroke. However, the underlying mechanisms at these loci in the pathogenesis of stroke and effective stroke drug targets are elusive. Therefore, we aimed to identify causal genes in the pathogenesis of str...

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Detalles Bibliográficos
Autores principales: Wu, Bang-Sheng, Chen, Shu-Fen, Huang, Shu-Yi, Ou, Ya-Nan, Deng, Yue-Ting, Chen, Shi-Dong, Dong, Qiang, Yu, Jin-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022281/
https://www.ncbi.nlm.nih.gov/pubmed/35449099
http://dx.doi.org/10.1186/s12967-022-03377-9