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Genetic Engineering and Enrichment of Human NK Cells for CAR-Enhanced Immunotherapy of Hematological Malignancies

The great clinical success of chimeric antigen receptor (CAR) T cells has unlocked new levels of immunotherapy for hematological malignancies. Genetically modifying natural killer (NK) cells as alternative CAR immune effector cells is also highly promising, as NK cells can be transplanted across HLA...

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Detalles Bibliográficos
Autores principales: Soldierer, Maren, Bister, Arthur, Haist, Corinna, Thivakaran, Aniththa, Cengiz, Sevgi Can, Sendker, Stephanie, Bartels, Nina, Thomitzek, Antonia, Smorra, Denise, Hejazi, Maryam, Uhrberg, Markus, Scheckenbach, Kathrin, Monzel, Cornelia, Wiek, Constanze, Reinhardt, Dirk, Niktoreh, Naghmeh, Hanenberg, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022481/
https://www.ncbi.nlm.nih.gov/pubmed/35464442
http://dx.doi.org/10.3389/fimmu.2022.847008