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The Major Autolysin Atl Regulates the Virulence of Staphylococcus aureus by Controlling the Sorting of LukAB

Infections caused by the Gram-positive bacterium Staphylococcus aureus remain a significant health threat globally. The production of bicomponent pore-forming leukocidins plays an important role in S. aureus pathogenesis. Transcriptionally, these toxins are primarily regulated by the Sae and Agr reg...

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Detalles Bibliográficos
Autores principales: Zheng, Xuhui, Ma, Sheya Xiao, St. John, Amelia, Torres, Victor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022505/
https://www.ncbi.nlm.nih.gov/pubmed/35258336
http://dx.doi.org/10.1128/iai.00056-22