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Target-Dependent Coordinated Biogenesis of Secondary MicroRNAs by miR-146a Balances Macrophage Activation Processes

MicroRNAs (miRNAs) repress protein expression by binding to the target mRNAs. Exploring whether the expression of one miRNA can regulate the abundance and activity of other miRNAs, we noted the coordinated biogenesis of miRNAs in activated macrophages. miRNAs with higher numbers of binding sites (th...

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Detalles Bibliográficos
Autores principales: Chatterjee, Susanta, Mukherjee, Ishita, Bhattacharjee, Shreya, Bose, Mainak, Chakrabarti, Saikat, Bhattacharyya, Suvendra N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022539/
https://www.ncbi.nlm.nih.gov/pubmed/35311564
http://dx.doi.org/10.1128/mcb.00452-21