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Whole-Genome Transformation of Yeast Promotes Rare Host Mutations with a Single Causative SNP Enhancing Acetic Acid Tolerance

Whole-genome (WG) transformation (WGT) with DNA from the same or another species has been used to obtain strains with superior traits. Very few examples have been reported in eukaryotes—most apparently involving integration of large fragments of foreign DNA into the host genome. We show that WGT of...

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Detalles Bibliográficos
Autores principales: Stojiljković, Marija, Claes, Arne, Deparis, Quinten, Demeke, Mekonnen M., Subotić, Ana, Foulquié-Moreno, María R., Thevelein, Johan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022575/
https://www.ncbi.nlm.nih.gov/pubmed/35311587
http://dx.doi.org/10.1128/mcb.00560-21