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Whole-Genome Transformation of Yeast Promotes Rare Host Mutations with a Single Causative SNP Enhancing Acetic Acid Tolerance
Whole-genome (WG) transformation (WGT) with DNA from the same or another species has been used to obtain strains with superior traits. Very few examples have been reported in eukaryotes—most apparently involving integration of large fragments of foreign DNA into the host genome. We show that WGT of...
Autores principales: | Stojiljković, Marija, Claes, Arne, Deparis, Quinten, Demeke, Mekonnen M., Subotić, Ana, Foulquié-Moreno, María R., Thevelein, Johan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022575/ https://www.ncbi.nlm.nih.gov/pubmed/35311587 http://dx.doi.org/10.1128/mcb.00560-21 |
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