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N,N-Dimethyldithiocarbamate Elicits Pneumococcal Hypersensitivity to Copper and Macrophage-Mediated Clearance

Streptococcus pneumoniae is a Gram-positive, encapsulated bacterium that is a significant cause of disease burden in pediatric and elderly populations. The rise in unencapsulated disease-causing strains and antimicrobial resistance in S. pneumoniae has increased the need for developing new antimicro...

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Detalles Bibliográficos
Autores principales: Menghani, Sanjay V., Cutcliffe, Madeline P., Sanchez-Rosario, Yamil, Pok, Chansorena, Watson, Alison, Neubert, Miranda J., Ochoa, Klariza, Wu, Hsin-Jung Joyce, Johnson, Michael D. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022595/
https://www.ncbi.nlm.nih.gov/pubmed/35311543
http://dx.doi.org/10.1128/iai.00597-21