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H1.0 C Terminal Domain Is Integral for Altering Transcription Factor Binding within Nucleosomes

[Image: see text] The linker histone H1 is a highly prevalent protein that compacts chromatin and regulates DNA accessibility and transcription. However, the mechanisms behind H1 regulation of transcription factor (TF) binding within nucleosomes are not well understood. Using in vitro fluorescence a...

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Detalles Bibliográficos
Autores principales: Burge, Nathaniel L., Thuma, Jenna L., Hong, Ziyong Z., Jamison, Kevin B., Ottesen, Jennifer J., Poirier, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022651/
https://www.ncbi.nlm.nih.gov/pubmed/35377618
http://dx.doi.org/10.1021/acs.biochem.2c00001