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H1.0 C Terminal Domain Is Integral for Altering Transcription Factor Binding within Nucleosomes
[Image: see text] The linker histone H1 is a highly prevalent protein that compacts chromatin and regulates DNA accessibility and transcription. However, the mechanisms behind H1 regulation of transcription factor (TF) binding within nucleosomes are not well understood. Using in vitro fluorescence a...
Autores principales: | Burge, Nathaniel L., Thuma, Jenna L., Hong, Ziyong Z., Jamison, Kevin B., Ottesen, Jennifer J., Poirier, Michael G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022651/ https://www.ncbi.nlm.nih.gov/pubmed/35377618 http://dx.doi.org/10.1021/acs.biochem.2c00001 |
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