Inhibitory mechanism of Ambroxol and Bromhexine Hydrochlorides as potent blockers of molecular interaction between SARS-CoV-2 spike protein and human angiotensin-converting Enzyme-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects the host cells through interaction of its spike protein with human angiotensin-converting enzyme 2 (hACE-2). High binding affinity between the viral spike protein and host cells hACE-2 receptor has been reported to enhance the vira...

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Detalles Bibliográficos
Autores principales: Kehinde, Idowu A., Egbejimi, Anu, Kaur, Manvir, Onyenaka, Collins, Adebusuyi, Tolulope, Olaleye, Omonike A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science, Inc 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022787/
https://www.ncbi.nlm.nih.gov/pubmed/35487151
http://dx.doi.org/10.1016/j.jmgm.2022.108201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022787/
https://www.ncbi.nlm.nih.gov/pubmed/35487151
http://dx.doi.org/10.1016/j.jmgm.2022.108201

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