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Inhibitory mechanism of Ambroxol and Bromhexine Hydrochlorides as potent blockers of molecular interaction between SARS-CoV-2 spike protein and human angiotensin-converting Enzyme-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects the host cells through interaction of its spike protein with human angiotensin-converting enzyme 2 (hACE-2). High binding affinity between the viral spike protein and host cells hACE-2 receptor has been reported to enhance the vira...
Autores principales: | Kehinde, Idowu A., Egbejimi, Anu, Kaur, Manvir, Onyenaka, Collins, Adebusuyi, Tolulope, Olaleye, Omonike A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science, Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022787/ https://www.ncbi.nlm.nih.gov/pubmed/35487151 http://dx.doi.org/10.1016/j.jmgm.2022.108201 |
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