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Validation-based model selection for (13)C metabolic flux analysis with uncertain measurement errors

Accurate measurements of metabolic fluxes in living cells are central to metabolism research and metabolic engineering. The gold standard method is model-based metabolic flux analysis (MFA), where fluxes are estimated indirectly from mass isotopomer data with the use of a mathematical model of the m...

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Detalles Bibliográficos
Autores principales: Sundqvist, Nicolas, Grankvist, Nina, Watrous, Jeramie, Mohit, Jain, Nilsson, Roland, Cedersund, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022838/
https://www.ncbi.nlm.nih.gov/pubmed/35404953
http://dx.doi.org/10.1371/journal.pcbi.1009999