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Validation-based model selection for (13)C metabolic flux analysis with uncertain measurement errors
Accurate measurements of metabolic fluxes in living cells are central to metabolism research and metabolic engineering. The gold standard method is model-based metabolic flux analysis (MFA), where fluxes are estimated indirectly from mass isotopomer data with the use of a mathematical model of the m...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022838/ https://www.ncbi.nlm.nih.gov/pubmed/35404953 http://dx.doi.org/10.1371/journal.pcbi.1009999 |