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Fangchinoline induces gallbladder cancer cell apoptosis by suppressing PI3K/Akt/XIAP axis

Gallbladder cancer (GBC) is the most common biliary tract malignancy with a dismal prognosis. The development of new drugs may help to improve prognosis. This study found that fangchinoline, a bisbenzylisoquinoline alkaloids, inhibited the proliferation and clone formation of GBC cells in a dose-dep...

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Detalles Bibliográficos
Autores principales: Li, Jiandong, Cen, Wenda, Tong, Chenhao, Wang, Luna, Zhang, Weiguang, Deng, Shiqing, Yu, Jianhua, Lu, Baochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022853/
https://www.ncbi.nlm.nih.gov/pubmed/35446864
http://dx.doi.org/10.1371/journal.pone.0266738