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NK cells and monocytes modulate primary HTLV-1 infection

We investigated the impact of monocytes, NK cells, and CD8(+) T-cells in primary HTLV-1 infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type (HTLV-1(WT)) or to the HTLV-1(p12KO) mutant unable to infect replete animals due to a single point mutation in orf-I that inhib...

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Detalles Bibliográficos
Autores principales: Moles, Ramona, Sarkis, Sarkis, Galli, Veronica, Omsland, Maria, Artesi, Maria, Bissa, Massimiliano, McKinnon, Katherine, Brown, Sophia, Hahaut, Vincent, Washington-Parks, Robyn, Welsh, Joshua, Venzon, David J., Gutowska, Anna, Doster, Melvin N., Breed, Matthew W., Killoran, Kristin E., Kramer, Joshua, Jones, Jennifer, Moniuszko, Marcin, Van den Broeke, Anne, Pise-Masison, Cynthia A., Franchini, Genoveffa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022856/
https://www.ncbi.nlm.nih.gov/pubmed/35377924
http://dx.doi.org/10.1371/journal.ppat.1010416