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Development and evaluation of ActSeq: A targeted next-generation sequencing panel for clinical oncology use

PURPOSE: The demand for high-throughput genetic profiling of somatic mutations in cancer tissues is growing. We sought to establish a targeted next generation sequencing (NGS) panel test for clinical oncology practice. METHODS: Customized probes were designed to capture exonic regions of 141 genes s...

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Detalles Bibliográficos
Autores principales: Shi, Zonggao, Lopez, Jacqueline, Kalliney, William, Sutton, Bobbie, Simpson, Joyce, Maggert, Kevin, Liu, Sheng, Wan, Jun, Stack, M. Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022865/
https://www.ncbi.nlm.nih.gov/pubmed/35446881
http://dx.doi.org/10.1371/journal.pone.0266914