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Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc

The heat-labile enterotoxins of Escherichia coli and cholera toxin of Vibrio cholerae are related in structure and function. Each of these oligomeric toxins is comprised of one A polypeptide and five B polypeptides. The B-subunits bind to gangliosides, which are followed by uptake into the intoxicat...

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Detalles Bibliográficos
Autores principales: Zalem, Dani, Juhás, Martin, Terrinoni, Manuela, King-Lyons, Natalie, Lebens, Michael, Varrot, Annabelle, Connell, Terry D, Teneberg, Susann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022906/
https://www.ncbi.nlm.nih.gov/pubmed/34972864
http://dx.doi.org/10.1093/glycob/cwab133