Cargando…

Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding?

In recent years, protein kinases have been one of the most pursued drug targets. These determined efforts have resulted in ever increasing numbers of small-molecule kinase inhibitors reaching to the market, offering novel treatment options for patients with distinct diseases. One essential component...

Descripción completa

Detalles Bibliográficos
Autores principales: Shevchenko, Ekaterina, Pantsar, Tatu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022976/
https://www.ncbi.nlm.nih.gov/pubmed/35226061
http://dx.doi.org/10.1042/BST20210837