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How lipids affect the energetics of co-translational alpha helical membrane protein folding

Membrane proteins need to fold with precision in order to function correctly, with misfolding potentially leading to disease. The proteins reside within a hydrophobic lipid membrane and must insert into the membrane and fold correctly, generally whilst they are being translated by the ribosome. Favo...

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Detalles Bibliográficos
Autores principales: Brady, Ryan, Harris, Nicola J., Pellowe, Grant A., Gulaidi Breen, Samuel, Booth, Paula J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022994/
https://www.ncbi.nlm.nih.gov/pubmed/35212365
http://dx.doi.org/10.1042/BST20201063