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An ultrasensitive UHPLC-ESI-MS/MS method augmented with a controlled microwave derivatization reaction for quantitation of vitamin D3 and its major metabolites in COVID-19 patients

It is established that vitamin D deficiency is correlated with the disease severity in COVID-19 patients. However, the reliable and sensitive quantitation of vitamin D3 (D3) and its metabolites remains a difficult challenge. Herein, a novel ultrasensitive and reliable UHPLC-ESI-MS/MS method was deve...

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Detalles Bibliográficos
Autores principales: Ahmed, Sameh A., Khojah, Hani M.J., Al-Thagfan, Sultan S., Alahmadi, Yaser M., Mohammed, Yasser A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023092/
https://www.ncbi.nlm.nih.gov/pubmed/35487016
http://dx.doi.org/10.1016/j.talanta.2022.123497