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TLR4 Agonist and Hypoxia Synergistically Promote the Formation of TLR4/NF-κB/HIF-1α Loop in Human Epithelial Ovarian Cancer

Inflammation and hypoxia are involved in numerous cancer progressions. Reportedly, the toll-like receptor 4 (TLR4)/nuclear factor kappa B (NF-κB) pathway and hypoxia-inducible factor-1α (HIF-1α) are activated and closely related to the chemoresistance and poor prognosis of epithelial ovarian cancer...

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Detalles Bibliográficos
Autores principales: Zhao, Bin, Niu, Xiulong, Huang, Suhui, Yang, Jing, Wei, Yiyi, Wang, Xiujuan, Wang, Junhong, Wang, Yue, Guo, Xiaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023210/
https://www.ncbi.nlm.nih.gov/pubmed/35464826
http://dx.doi.org/10.1155/2022/4201262