Synthesis, Characterization, and In Vivo Cytokinome Profile of IL-12-Loaded PLGA Nanospheres

We report the successful encapsulation and elution of recombinant murine IL-12 (rmIL-12) from poly(lactide-co-glycolic) acid (PLGA) nanospheres (IL-12-NS) synthesized using the double emulsion/solvent evaporation (DESE) technique with microsphere depletion through ultracentrifugation. Images obtaine...

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Detalles Bibliográficos
Autores principales: Lacinski, Ryan A., Markel, Justin E., Noore, Jabeen, Pratt, Hillary G., Lindsey, Brock A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023212/
https://www.ncbi.nlm.nih.gov/pubmed/35465347
http://dx.doi.org/10.1155/2022/6993187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023212/
https://www.ncbi.nlm.nih.gov/pubmed/35465347
http://dx.doi.org/10.1155/2022/6993187

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