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Development of a genome-targeting mutator for the adaptive evolution of microbial cells
Methods that can randomly introduce mutations in the microbial genome have been used for classical genetic screening and, more recently, the evolutionary engineering of microbial cells. However, most methods rely on either cell-damaging agents or disruptive mutations of genes that are involved in ac...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023256/ https://www.ncbi.nlm.nih.gov/pubmed/34928386 http://dx.doi.org/10.1093/nar/gkab1244 |