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ZWC complex-mediated SPT5 phosphorylation suppresses divergent antisense RNA transcription at active gene promoters

The human genome encodes large numbers of non-coding RNAs, including divergent antisense transcripts at transcription start sites (TSSs). However, molecular mechanisms by which divergent antisense transcription is regulated have not been detailed. Here, we report a novel ZWC complex composed of ZC3H...

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Detalles Bibliográficos
Autores principales: Park, Kihyun, Zhong, Jian, Jang, Jin Sung, Kim, Jihyun, Kim, Hye-Jung, Lee, Jeong-Heon, Kim, Jaehoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023261/
https://www.ncbi.nlm.nih.gov/pubmed/35325203
http://dx.doi.org/10.1093/nar/gkac193