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ZWC complex-mediated SPT5 phosphorylation suppresses divergent antisense RNA transcription at active gene promoters

The human genome encodes large numbers of non-coding RNAs, including divergent antisense transcripts at transcription start sites (TSSs). However, molecular mechanisms by which divergent antisense transcription is regulated have not been detailed. Here, we report a novel ZWC complex composed of ZC3H...

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Detalles Bibliográficos
Autores principales:	Park, Kihyun, Zhong, Jian, Jang, Jin Sung, Kim, Jihyun, Kim, Hye-Jung, Lee, Jeong-Heon, Kim, Jaehoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023261/ https://www.ncbi.nlm.nih.gov/pubmed/35325203 http://dx.doi.org/10.1093/nar/gkac193

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