The nucleoporin Gle1 activates DEAD-box protein 5 (Dbp5) by promoting ATP binding and accelerating rate limiting phosphate release

The DEAD-box protein Dbp5 is essential for RNA export, which involves regulation by the nucleoporins Gle1 and Nup159 at the cytoplasmic face of the nuclear pore complex (NPC). Mechanistic understanding of how these nucleoporins regulate RNA export requires analyses of the intrinsic and activated Dbp...

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Detalles Bibliográficos
Autores principales: Gray, Shawn, Cao, Wenxiang, Montpetit, Ben, De La Cruz, Enrique M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023272/
https://www.ncbi.nlm.nih.gov/pubmed/35286399
http://dx.doi.org/10.1093/nar/gkac164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023272/
https://www.ncbi.nlm.nih.gov/pubmed/35286399
http://dx.doi.org/10.1093/nar/gkac164

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