hnRNP G/RBMX enhances HPV16 E2 mRNA splicing through a novel splicing enhancer and inhibits production of spliced E7 oncogene mRNAs

Human papillomavirus type 16 (HPV16) E2 is an essential HPV16 protein. We have investigated how HPV16 E2 expression is regulated and have identifed a splicing enhancer that is required for production of HPV16 E2 mRNAs. This uridine-less splicing enhancer sequence (ACGAGGACGAGGACAAGGA) contains 84% a...

Descripción completa

Detalles Bibliográficos
Autores principales: Hao, Chengyu, Zheng, Yunji, Jönsson, Johanna, Cui, Xiaoxu, Yu, Haoran, Wu, Chengjun, Kajitani, Naoko, Schwartz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023273/
https://www.ncbi.nlm.nih.gov/pubmed/35357488
http://dx.doi.org/10.1093/nar/gkac213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023273/
https://www.ncbi.nlm.nih.gov/pubmed/35357488
http://dx.doi.org/10.1093/nar/gkac213

Ejemplares similares