Long promoter sequences form higher-order G-quadruplexes: an integrative structural biology study of c-Myc, k-Ras and c-Kit promoter sequences

We report on higher-order G-quadruplex structures adopted by long promoter sequences obtained by an iterative integrated structural biology approach. Our approach uses quantitative biophysical tools (analytical ultracentrifugation, small-angle X-ray scattering, and circular dichroism spectroscopy) c...

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Detalles Bibliográficos
Autores principales: Monsen, Robert C, DeLeeuw, Lynn W, Dean, William L, Gray, Robert D, Chakravarthy, Srinivas, Hopkins, Jesse B, Chaires, Jonathan B, Trent, John O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023277/
https://www.ncbi.nlm.nih.gov/pubmed/35325198
http://dx.doi.org/10.1093/nar/gkac182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023277/
https://www.ncbi.nlm.nih.gov/pubmed/35325198
http://dx.doi.org/10.1093/nar/gkac182

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