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Coordinated changes in gene expression, H1 variant distribution and genome 3D conformation in response to H1 depletion

Up to seven members of the histone H1 family may contribute to chromatin compaction and its regulation in human somatic cells. In breast cancer cells, knock-down of multiple H1 variants deregulates many genes, promotes the appearance of genome-wide accessibility sites and triggers an interferon resp...

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Detalles Bibliográficos
Autores principales: Serna-Pujol, Núria, Salinas-Pena, Mónica, Mugianesi, Francesca, Le Dily, François, Marti-Renom, Marc A, Jordan, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023279/
https://www.ncbi.nlm.nih.gov/pubmed/35380694
http://dx.doi.org/10.1093/nar/gkac226