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Coordinated changes in gene expression, H1 variant distribution and genome 3D conformation in response to H1 depletion
Up to seven members of the histone H1 family may contribute to chromatin compaction and its regulation in human somatic cells. In breast cancer cells, knock-down of multiple H1 variants deregulates many genes, promotes the appearance of genome-wide accessibility sites and triggers an interferon resp...
Autores principales: | Serna-Pujol, Núria, Salinas-Pena, Mónica, Mugianesi, Francesca, Le Dily, François, Marti-Renom, Marc A, Jordan, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023279/ https://www.ncbi.nlm.nih.gov/pubmed/35380694 http://dx.doi.org/10.1093/nar/gkac226 |
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