Molecular basis for human mitochondrial tRNA m(3)C modification by alternatively spliced METTL8

METTL8 has recently been identified as the methyltransferase catalyzing 3-methylcytidine biogenesis at position 32 (m(3)C32) of mitochondrial tRNAs. METTL8 also potentially participates in mRNA methylation and R-loop biogenesis. How METTL8 plays multiple roles in distinct cell compartments and catal...

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Detalles Bibliográficos
Autores principales: Huang, Meng-Han, Peng, Gui-Xin, Mao, Xue-Ling, Wang, Jin-Tao, Zhou, Jing-Bo, Zhang, Jian-Hui, Chen, Meirong, Wang, En-Duo, Zhou, Xiao-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023283/
https://www.ncbi.nlm.nih.gov/pubmed/35357504
http://dx.doi.org/10.1093/nar/gkac184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023283/
https://www.ncbi.nlm.nih.gov/pubmed/35357504
http://dx.doi.org/10.1093/nar/gkac184

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