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CRISPR–Cas9 gRNA efficiency prediction: an overview of predictive tools and the role of deep learning

The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) system has become a successful and promising technology for gene-editing. To facilitate its effective application, various computational tools have been developed. These tools can assist research...

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Detalles Bibliográficos
Autores principales: Konstantakos, Vasileios, Nentidis, Anastasios, Krithara, Anastasia, Paliouras, Georgios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023298/
https://www.ncbi.nlm.nih.gov/pubmed/35349718
http://dx.doi.org/10.1093/nar/gkac192