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Distinct immune cell dynamics correlate with the immunogenicity and reactogenicity of SARS-CoV-2 mRNA vaccine

Two doses of Pfizer/BioNTech BNT162b2 mRNA vaccine elicit robust severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing antibodies with frequent adverse events. Here, by applying a high-dimensional immune profiling on 92 vaccinees, we identify six vaccine-induced immune dynamics t...

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Detalles Bibliográficos
Autores principales: Takano, Tomohiro, Morikawa, Miwa, Adachi, Yu, Kabasawa, Kiyomi, Sax, Nicolas, Moriyama, Saya, Sun, Lin, Isogawa, Masanori, Nishiyama, Ayae, Onodera, Taishi, Terahara, Kazutaka, Tonouchi, Keisuke, Nishimura, Masashi, Tomii, Kentaro, Yamashita, Kazuo, Matsumura, Takayuki, Shinkai, Masaharu, Takahashi, Yoshimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023335/
https://www.ncbi.nlm.nih.gov/pubmed/35545084
http://dx.doi.org/10.1016/j.xcrm.2022.100631