Amphiphilic anti-SARS-CoV-2 drug remdesivir incorporates into the lipid bilayer and nerve terminal membranes influencing excitatory and inhibitory neurotransmission

Remdesivir is a novel antiviral drug, which is active against the SARS-CoV-2 virus. Remdesivir is known to accumulate in the brain but it is not clear whether it influences the neurotransmission. Here we report diverse and pronounced effects of remdesivir on transportation and release of excitatory...

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Detalles Bibliográficos
Autores principales: Krisanova, Natalia, Pozdnyakova, Natalia, Pastukhov, Artem, Dudarenko, Marina, Shatursky, Oleg, Gnatyuk, Olena, Afonina, Uliana, Pyrshev, Kyrylo, Dovbeshko, Galina, Yesylevskyy, Semen, Borisova, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023372/
https://www.ncbi.nlm.nih.gov/pubmed/35461828
http://dx.doi.org/10.1016/j.bbamem.2022.183945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023372/
https://www.ncbi.nlm.nih.gov/pubmed/35461828
http://dx.doi.org/10.1016/j.bbamem.2022.183945

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