Gene fusions and oncogenic mutations in MLH1 deficient and BRAFV600E wild-type colorectal cancers

Gene fusions can act as oncogenic drivers and offer targets for cancer therapy. Since fusions are rare in colorectal cancer (CRC), their universal screening seems impractical. Our aim was to investigate gene fusions in 62 CRC cases with deficient MLH1 (dMLH1) and BRAFV600E wild-type (wt) status from...

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Detalles Bibliográficos
Autores principales: Ukkola, Iiris, Nummela, Pirjo, Kero, Mia, Tammio, Hanna, Tuominen, Jenni, Kairisto, Veli, Kallajoki, Markku, Haglund, Caj, Peltomäki, Päivi, Kytölä, Soili, Ristimäki, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023403/
https://www.ncbi.nlm.nih.gov/pubmed/35237889
http://dx.doi.org/10.1007/s00428-022-03302-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023403/
https://www.ncbi.nlm.nih.gov/pubmed/35237889
http://dx.doi.org/10.1007/s00428-022-03302-x

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