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Behavioral and slice electrophysiological assessment of DREADD ligand, deschloroclozapine (DCZ) in rats

Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) have become a premier neuroscience research tool for enabling reversible manipulations of cellular activity following experimenter-controlled delivery of a DREADD-specific ligand. However, several DREADD ligands, e.g., clozapine-N-...

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Detalles Bibliográficos
Autores principales: Nentwig, Todd B., Obray, J. Daniel, Vaughan, Dylan T., Chandler, L. Judson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023443/
https://www.ncbi.nlm.nih.gov/pubmed/35449195
http://dx.doi.org/10.1038/s41598-022-10668-0