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Proteome-wide landscape of solubility limits in a bacterial cell

Proteins are prone to aggregate when expressed above their solubility limits. Aggregation may occur rapidly, potentially as early as proteins emerge from the ribosome, or slowly, following synthesis. However, in vivo data on aggregation rates are scarce. Here, we classified the Escherichia coli prot...

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Detalles Bibliográficos
Autores principales: Györkei, Ádám, Daruka, Lejla, Balogh, Dávid, Őszi, Erika, Magyar, Zoltán, Szappanos, Balázs, Fekete, Gergely, Fuxreiter, Mónika, Horváth, Péter, Pál, Csaba, Kintses, Bálint, Papp, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023497/
https://www.ncbi.nlm.nih.gov/pubmed/35449391
http://dx.doi.org/10.1038/s41598-022-10427-1