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Ketone-selenoesters as potential anticancer and multidrug resistance modulation agents in 2D and 3D ovarian and breast cancer in vitro models

Long-term treatment of cancer with chemotherapeutics leads to the development of resistant forms that reduce treatment options. The main associated mechanism is the overexpression of transport proteins, particularly P-glycoprotein (P-gp, ABCB1). In this study, we have tested the anticancer and multi...

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Detalles Bibliográficos
Autores principales: Dobiasová, Simona, Szemerédi, Nikoletta, Kučerová, Denisa, Koucká, Kamila, Václavíková, Radka, Gbelcová, Helena, Ruml, Tomáš, Domínguez-Álvarez, Enrique, Spengler, Gabriella, Viktorová, Jitka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023544/
https://www.ncbi.nlm.nih.gov/pubmed/35449387
http://dx.doi.org/10.1038/s41598-022-10311-y