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HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis

Perineural invasion (PNI) is a pathologic feature of pancreatic cancer and is associated with poor outcomes, metastasis, and recurrence in pancreatic cancer patients. However, the molecular mechanism of PNI remains unclear. The present study aimed to investigate the mechanism that HGF/c-Met pathway...

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Detalles Bibliográficos
Autores principales: Qin, Tao, Xiao, Ying, Qian, Weikun, Wang, Xueni, Gong, Mengyuan, Wang, Qiqi, An, Rui, Han, Liang, Duan, Wanxing, Ma, Qingyong, Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023560/
https://www.ncbi.nlm.nih.gov/pubmed/35449152
http://dx.doi.org/10.1038/s41419-022-04799-5