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Persistent immunogenicity of integrase defective lentiviral vectors delivering membrane-tethered native-like HIV-1 envelope trimers

Integrase Defective Lentiviral Vectors (IDLVs) represent an attractive vaccine platform for delivering HIV-1 antigens, given their ability to induce specific and persistent immune responses in both mice and non-human primates (NHPs). Recent advances in HIV-1 immunogen design demonstrated that native...

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Detalles Bibliográficos
Autores principales: Gallinaro, Alessandra, Pirillo, Maria Franca, Aldon, Yoann, Cecchetti, Serena, Michelini, Zuleika, Tinari, Antonella, Borghi, Martina, Canitano, Andrea, McKay, Paul F., Bona, Roberta, Vescio, Maria Fenicia, Grasso, Felicia, Blasi, Maria, Baroncelli, Silvia, Scarlatti, Gabriella, LaBranche, Celia, Montefiori, David, Klotman, Mary E., Sanders, Rogier W., Shattock, Robin J., Negri, Donatella, Cara, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023570/
https://www.ncbi.nlm.nih.gov/pubmed/35449174
http://dx.doi.org/10.1038/s41541-022-00465-1