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ACE2, Circumventricular Organs and the Hypothalamus, and COVID-19

The SARS-CoV-2 virus gains entry to cells by binding to angiotensin-converting enzyme 2 (ACE2). Since circumventricular organs and parts of the hypothalamus lack a blood–brain barrier, and immunohistochemical studies demonstrate that ACE2 is highly expressed in circumventricular organs which are int...

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Detalles Bibliográficos
Autores principales: Ong, Wei-Yi, Satish, R. L., Herr, Deron R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023728/
https://www.ncbi.nlm.nih.gov/pubmed/35451691
http://dx.doi.org/10.1007/s12017-022-08706-1