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Cell Type Diversity Statistic: An Entropy-Based Metric to Compare Overall Cell Type Composition Across Samples

Changes of cell type composition across samples can carry biological significance and provide insight into disease and other conditions. Single cell transcriptomics has made it possible to study cell type composition at a fine resolution. Most single cell studies investigate compositional changes be...

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Detalles Bibliográficos
Autores principales: Karagiannis, Tanya T, Monti, Stefano, Sebastiani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023789/
https://www.ncbi.nlm.nih.gov/pubmed/35464841
http://dx.doi.org/10.3389/fgene.2022.855076