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WNT16B enhances the proliferation and self-renewal of limbal epithelial cells via CXCR4/MEK/ERK signaling

Culture of limbal epithelial cells (LECs) provides the principal source of transplanted limbal stem cells (LESCs) for treatment of limbal-stem-cell deficiency. Optimization of the culture conditions for in-vitro-expanded LECs will help to create a graft with an optimized quality and quantity of LESC...

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Detalles Bibliográficos
Autores principales: Zhao, Songjiao, Wan, Xichen, Dai, Yiqin, Gong, Lan, Le, Qihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023808/
https://www.ncbi.nlm.nih.gov/pubmed/35364008
http://dx.doi.org/10.1016/j.stemcr.2022.03.001