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GP2-enriched pancreatic progenitors give rise to functional beta cells in vivo and eliminate the risk of teratoma formation

Human pluripotent stem cell (hPSC)-derived pancreatic progenitors (PPs) can be differentiated into beta-like cells in vitro and in vivo and therefore have therapeutic potential for type 1 diabetes (T1D) treatment. However, the purity of PPs varies across different hPSC lines, differentiation protoco...

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Detalles Bibliográficos
Autores principales: Aghazadeh, Yasaman, Sarangi, Farida, Poon, Frankie, Nkennor, Blessing, McGaugh, Emily C., Nunes, Sara S., Nostro, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023812/
https://www.ncbi.nlm.nih.gov/pubmed/35364010
http://dx.doi.org/10.1016/j.stemcr.2022.03.004