Cargando…

GP2-enriched pancreatic progenitors give rise to functional beta cells in vivo and eliminate the risk of teratoma formation

Human pluripotent stem cell (hPSC)-derived pancreatic progenitors (PPs) can be differentiated into beta-like cells in vitro and in vivo and therefore have therapeutic potential for type 1 diabetes (T1D) treatment. However, the purity of PPs varies across different hPSC lines, differentiation protoco...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aghazadeh, Yasaman, Sarangi, Farida, Poon, Frankie, Nkennor, Blessing, McGaugh, Emily C., Nunes, Sara S., Nostro, M. Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023812/ https://www.ncbi.nlm.nih.gov/pubmed/35364010 http://dx.doi.org/10.1016/j.stemcr.2022.03.004

Ejemplares similares

Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
por: Cogger, Kathryn F., et al.
Publicado: (2017)

CaveCrawler: an interactive analysis suite for cavefish bioinformatics
por: Perry, Annabel, et al.
Publicado: (2022)

Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals
por: Yung, Theodora, et al.
Publicado: (2019)

Monocyte progenitors give rise to multinucleated giant cells
por: Lösslein, Anne Kathrin, et al.
Publicado: (2021)

Identification of bipotent progenitors that give rise to myogenic and connective tissues in mouse
por: Grimaldi, Alexandre, et al.
Publicado: (2022)

Inducible Forward Programming of Human Pluripotent Stem Cells to Hemato-endothelial Progenitor Cells with Hematopoietic Progenitor Potential
por: Lange, Lucas, et al.
Publicado: (2019)

Pomc-expressing progenitors give rise to antagonistic populations in hypothalamic feeding circuits
por: Padilla, Stephanie L., et al.
Publicado: (2010)

Network-Based Genomic Analysis of Human Oligodendrocyte Progenitor Differentiation
por: Pol, Suyog U., et al.
Publicado: (2017)

Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis
por: Van Keymeulen, Alexandra, et al.
Publicado: (2009)

Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum
por: Chung, S-H, et al.
Publicado: (2013)

Identification of renin progenitors in the mouse bone marrow that give rise to B-cell leukaemia
por: Belyea, Brian C., et al.
Publicado: (2014)

Fgf10(+) progenitors give rise to the chick hypothalamus by rostral and caudal growth and differentiation
por: Fu, Travis, et al.
Publicado: (2017)

Erythromyeloid progenitors give rise to a population of osteoclasts contributing to bone homeostasis and repair
por: Yahara, Yasuhito, et al.
Publicado: (2020)

CDC commentary: don't give in and give those antibiotics!
Publicado: (2019)

Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors
por: Krentz, Nicole A.J., et al.
Publicado: (2018)

Generation of pancreatic progenitors from human pluripotent stem cells by small molecules
por: Jiang, Yuqian, et al.
Publicado: (2021)

Defined Conditions for the Isolation and Expansion of Basal Prostate Progenitor Cells of Mouse and Human Origin
por: Höfner, Thomas, et al.
Publicado: (2015)

Sequence and expression levels of circular RNAs in progenitor cell types during mouse corticogenesis
por: Dori, Martina, et al.
Publicado: (2019)

Derivation and Expansion of PAX7-Positive Muscle Progenitors from Human and Mouse Embryonic Stem Cells
por: Shelton, Michael, et al.
Publicado: (2014)

Transcriptome-wide Profiling and Posttranscriptional Analysis of Hematopoietic Stem/Progenitor Cell Differentiation toward Myeloid Commitment
por: Klimmeck, Daniel, et al.
Publicado: (2014)

Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium
por: Salomonis, Nathan, et al.
Publicado: (2016)

Differentiation of Human Embryonic Stem Cells to Endothelial Progenitor Cells on Laminins in Defined and Xeno-free Systems
por: Nguyen, Mien T.X., et al.
Publicado: (2016)

Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development
por: Roy, Anindita, et al.
Publicado: (2021)

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex
por: Ulmke, Pauline Antonie, et al.
Publicado: (2021)

Unbalanced distribution of materials: the art of giving rise to hepatocytes from liver stem/progenitor cells
por: Liu, Wei-Hui, et al.
Publicado: (2014)

Modified Newtonian Dynamics (MOND): Observational Phenomenology and Relativistic Extensions
por: Famaey, Benoît, et al.
Publicado: (2012)

Dynamic Analysis of Gene Expression and Genome-wide Transcription Factor Binding during Lineage Specification of Multipotent Progenitors
por: May, Gillian, et al.
Publicado: (2013)

Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells
por: Santos, Renata, et al.
Publicado: (2017)

Analysis of Differentiation Protocols Defines a Common Pancreatic Progenitor Molecular Signature and Guides Refinement of Endocrine Differentiation
por: Wesolowska-Andersen, Agata, et al.
Publicado: (2019)

Isolation of Progenitors that Exhibit Myogenic/Osteogenic Bipotency In Vitro by Fluorescence-Activated Cell Sorting from Human Fetal Muscle
por: Castiglioni, Alessandra, et al.
Publicado: (2014)

Characterization of Epithelial Progenitors in Normal Human Palatine Tonsils and Their HPV16 E6/E7-Induced Perturbation
por: Kang, Sung Yoon Catherine, et al.
Publicado: (2015)

Long-term feeder-free culture of human pancreatic progenitors on fibronectin or matrix-free polymer potentiates β cell differentiation
por: Nakamura, Akiko, et al.
Publicado: (2022)

Intermediate progenitor cells provide a transition between hematopoietic progenitors and their differentiated descendants
por: Spratford, Carrie M., et al.
Publicado: (2021)

A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients
por: Jiang, Jia Xin, et al.
Publicado: (2021)

Dropsy, and the Pathological Conditions That Give Rise to It
por: Davis, N. S.
Publicado: (1863)

Muscle-Bound Primordial Stem Cells Give Rise to Myofiber-Associated Myogenic and Non-Myogenic Progenitors
por: Segev, Elad, et al.
Publicado: (2011)

bayroot: Bayesian sampling of HIV-1 integration dates by root-to-tip regression
por: Ferreira, Roux-Cil, et al.
Publicado: (2022)

Stem Cells, Self-Renewal, and Lineage Commitment in the Endocrine System
por: Mariniello, Katia, et al.
Publicado: (2019)

HexSE: Simulating evolution in overlapping reading frames
por: Muñoz-Baena, Laura, et al.
Publicado: (2023)

Linkage disequilibrium network analysis (LDna) gives a global view of chromosomal inversions, local adaptation and geographic structure
por: Kemppainen, Petri, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_govl9od6bje1fomrircvbmd3v7