HINT: Hierarchical interaction network for clinical-trial-outcome predictions

Clinical trials are crucial for drug development but often face uncertain outcomes due to safety, efficacy, or patient-recruitment problems. We propose the Hierarchical Interaction Network (HINT) to predict clinical trial outcomes. First, HINT encodes multi-modal data (drug molecule, target disease,...

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Detalles Bibliográficos
Autores principales: Fu, Tianfan, Huang, Kexin, Xiao, Cao, Glass, Lucas M., Sun, Jimeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024011/
https://www.ncbi.nlm.nih.gov/pubmed/35465223
http://dx.doi.org/10.1016/j.patter.2022.100445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024011/
https://www.ncbi.nlm.nih.gov/pubmed/35465223
http://dx.doi.org/10.1016/j.patter.2022.100445

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