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Quantitative Water Permeability Mapping of Blood-Brain-Barrier Dysfunction in Aging

Blood-brain-barrier (BBB) dysfunction is a hallmark of aging and aging-related disorders, including cerebral small vessel disease and Alzheimer’s disease. An emerging biomarker of BBB dysfunction is BBB water exchange rate (k(W)) as measured by diffusion-weighted arterial spin labeling (DW-ASL) MRI....

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Detalles Bibliográficos
Autores principales: Ford, Jeremy N., Zhang, Qihao, Sweeney, Elizabeth M., Merkler, Alexander E., de Leon, Mony J., Gupta, Ajay, Nguyen, Thanh D., Ivanidze, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024318/
https://www.ncbi.nlm.nih.gov/pubmed/35462701
http://dx.doi.org/10.3389/fnagi.2022.867452