Identification of Zinc-Binding Inhibitors of Matrix Metalloproteinase-9 to Prevent Cancer Through Deep Learning and Molecular Dynamics Simulation Approach

The overexpression of matrix metalloproteinase-9 (MMP-9) is associated with tumor development and angiogenesis, and hence, it has been considered an attractive drug target for anticancer therapy. To assist in drug design endeavors for MMP-9 targets, an in silico study was presented to investigate wh...

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Detalles Bibliográficos
Autores principales: Mathpal, Shalini, Sharma, Priyanka, Joshi, Tushar, Pande, Veena, Mahmud, Shafi, Jeong, Mi-Kyung, Obaidullah, Ahmad J., Chandra, Subhash, Kim, Bonglee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024349/
https://www.ncbi.nlm.nih.gov/pubmed/35463960
http://dx.doi.org/10.3389/fmolb.2022.857430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024349/
https://www.ncbi.nlm.nih.gov/pubmed/35463960
http://dx.doi.org/10.3389/fmolb.2022.857430

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